Goals

To replace blood draws with accessible monitoring by developing new modalities to detect and monitor diseases beyond what is currently detectable.

Background and Current Landscape

Diagnostics primarily rely on an invasive sample collection for analysis, most commonly blood. Blood serves as the window into the body’s biological state but collecting blood requires a trained professional to conduct the blood draw and a clinic to process the sample. The extent of measurable health metrics is constrained by the absence of innovations that can measure biological analytes through the skin. In addition, reliable continuous monitoring requires hospital-grade machines which are both expensive, non-portable, and require invasive or semi-invasive placement to access the blood stream. The ability to non-invasively collect biological information through detection of electromagnetic signals would expand both the accessibility and throughput of disease detection and monitoring.

Investments in this subdomain support innovative approaches to non-invasive analyte detection that expand sensing capabilities for low-resource settings beyond what is currently detectable, using techniques such as: hyperspectral imaging, Raman spectroscopy, and ultrasound. Low-cost, portable, rapid, and non-invasive tools will allow for rapid screening of populations to screen and triage individuals at risk.

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